A COMPARATIVE LIFE CYCLE ASSESSMENT OF FIBER-REINFORCED POLYMERS AS A SUSTAINABLE REINFORCEMENT OPTION IN CONCRETE BEAMS

A comparative life cycle assessment of fiber-reinforced polymers as a sustainable reinforcement option in concrete beams

Environmental awareness and the need for sustainable construction inspired researchers and practitioners to explore innovative alternatives that might reduce greenhouse gas emissions and energy use related to excessive structural work.One such alternative is the utilization of Fiber-Reinforced Polymer (FRP) bars as a reinforcement in reinforced con

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Melatonin: An Anti-Tumor Agent in Hormone-Dependent Cancers

Melatonin (N-acetyl-5-methoxytryptamine) is a hormone synthesized and secreted by the pineal gland mainly during the night, since light exposure suppresses its production.Initially, an implication of this indoleamine in malignant disease was described in endocrine-responsive breast cancer.Data from several clinical trials and multiple experimental

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Targeting SRSF2 mutations in leukemia with RKI-1447: A strategy to impair cellular division and nuclear structure

Summary: Spliceosome machinery mutations are common early mutations in myeloid malignancies; however, effective targeted therapies against them are still lacking.In the current study, we used an in vitro high-throughput drug screen among four different isogenic cell lines and identified RKI-1447, a Rho-associated protein kinase inhibitor, as select

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